My laboratory is interested in how keratinocytes sense and respond to changes in their physical microenvironment. We employ engineered materials and model systems to precisely control the signals presented to cells.
Key projects include:
(1) The role of biophysical cues in epidermal fate decisions.
(2) The influence of substrate mechanics and topography on wound healing.
(3) Transcriptional regulators of mechano-transduction in keratinocytes.
We also have an on-going interest in tissue engineering and regenerative medicine, and a long-term goal for our research is to translate our findings into effective strategies for skin repair.