Nicola Casali

Title: Dr
Postdoctoral Research Assistant

Nicola’s research focuses on using whole genome sequence analysis to understand aspects of tuberculosis epidemiology and drug resistance.

She is also collaborating with commercial partners in the development of a novel diagnostic for MDR/ XDR TB.

Recent and ongoing research projects:
  • Development and verification of a novel technology to detect and monitor multi-drug resistant tuberculosis.
  • Genetic analysis of the host-pathogen interaction in tuberculosis


Nicola Casali gained her PhD at the London School of Hygiene & Tropical Medicine where she investigated gene regulation in M. tuberculosis. Subsequently, she spent nine years working at the University of California, Berkeley studying the role of genes involved in tuberculosis pathogenesis. She joined the Blizard Institute as a Postdoctoral Researcher in 2008.



M. tuberculosis pathogenesis, genomics and drug resistance


Casali, N, Riley LW (2007) A phylogenomic analysis of the Actinomycetales mce operons. BMC Genomics 8:60.

Casali N, White AM, Riley LW (2006) Regulation of the Mycobacterium tuberculosis mce1 operon. J Bacteriol 188:441-449.

Casali N, Konieczny M, Schmidt MA, Riley LW (2002) Invasion activity of a Mycobacterium tuberculosis peptide presented by the Escherichia coli AIDA autotransporter. Infect Immun 70: 6846-6852.



Centre for Immunology and Infectious Disease
Blizard Institute
Barts and The London School of Medicine and Dentistry
Blizard Building
4 Newark Street
E1 2AT

020 78822575
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