Mark Scott has a BSc in Physiology and Biology, and was awarded a PhD in Physiology / Medicine from the University of London in 1998 for his work on “Prolonged monitoring of colonic motor activity by an ambulatory recording technique”. He has long experience, both clinical and academic, related to the physiological investigation of functional (primarily lower) gastrointestinal disorders, and was integral to setting up the GI Physiology Unit at the Royal London Hospital in 1994. He is now Co-Director of the Unit, together with Professor Daniel Sifrim. The Unit is internationally renowned, and provides a clinical service to more than 2,500 patients per year, which supplies the resources for aligned research; there are currently 20 full-time and affiliated staff members.
Mark is the author of over 90 peer-reviewed publications, 8 book chapters, and has recently been Guest Editor of 2 journal supplements dedicated to the subject of chronic constipation. Together with Professor Charles Knowles and Mr Peter Lunniss, he leads a flourishing research programme centered on clinical GI (principally colorectal) physiological investigation, involving the supervision of several research fellows. Originating in a fundamental philosophy of carefully phenotyping patients through comprehensive investigation, the group’s pioneering work on visceral hyposensitivity has gained international recognition. A further principal research interest, particularly through collaboration with Dr Phil Dinning (Adelaide), concerns assessment of pancolonic motor function using novel methodologies.
Recent and ongoing research projects:
- The role of rectal hyposensation in the development of chronic functional constipation: an examination of the sensory and motor pathways of the rectum
- Colorectal motility in health and disease
- Optimising outcomes in sacral nerve stimulation