Prof Priestley works on the anatomy and neurochemistry of dorsal root ganglion (DRG) neurons and spinal cord neurons, with a particular focus on their response to injury and the organization of pain pathways. Much of this work involves sophisticated techniques for localizing and imaging biomolecules in tissue sections, together with experimental studies manipulating spinal cord and peripheral nerves in vivo. His work on the neurochemical properties of DRG neurons has revealed important principles concerning the regulation of DRG neurons by target-derived and injury-derived growth factors. Prof Priestley also has a strong track record of studies on spinal cord injury. Current work focuses on the development of biomaterial-based conduits for peripheral nerve and spinal cord repair, and the development and evaluation of novel neuroprotective agents. Prof Priestley is founder-director of Neurotex, a spin-off company established by QMUL to develop work with novel conduits for peripheral nerve repair which are based on spider-like silks.